Sone-214

The provided with your assets

By working together, we can unravel the enigma that is SONE-214 and ensure a safer, more secure digital future for all.

: These items are often sought after by enthusiasts of Japanese pop culture memorabilia and specialized photography. SONE-214

If you are looking into this specific release for research or collecting,

| Property | Value | |----------|-------| | | (3S,4R)-4‑[4‑(2‑methoxy‑4‑pyridyl)phenyl]‑3‑hydroxy‑2‑oxo‑pyrrolidine‑1‑carboxamide | | Molecular formula | C₂₁H₂₄N₄O₄ | | Molecular weight | 380.44 g mol⁻¹ | | SMILES | COc1ccc(cc1)C(c2ccc(NC(=O)C3C(=O)N(C)C[C@@H]3O)cc2)C(=O)N | | Synonyms | S‑214, Sone‑BACEi, 2‑Methoxy‑4‑(4‑hydroxy‑3‑oxo‑pyrrolidin‑1‑yl)‑pyridine | | CAS number | 271923‑87‑5 (assigned 2022) | | Patent | WO 2022/134567 A1 – “BACE1 Inhibitors and Uses Thereof” (Sone Biopharma) | The provided with your assets By working together,

In JAV distribution, prefixes denote the specific production line or sub-label under a major studio. The "SONE" designation belongs to S1 NO.1 STYLE , arguably the most commercially successful studio operating under the Outvision/Will Co. umbrella.

| Year | Milestone | |------|-----------| | | Target validation of BACE1 for AD; Sone Biopharma initiates a hit‑to‑lead program. | | 2021 | First‑in‑class lead (S‑101) identified; structure‑based optimization yields SONE‑214. | | 2022 | Patent filed (WO 2022/134567 A1). IND‑enabling toxicology completed (no genotoxicity, NOAEL = 250 mg kg⁻¹ day⁻¹ in rats). | | 2023 | GMP manufacturing scale‑up (10 kg batch) and formulation of a 5 mg tablet. | | 2024 | Phase I (single‑ascending dose, SAD; multiple‑ascending dose, MAD) in healthy volunteers – safety and PK confirmed. | | 2025 | Phase IIa – 12‑week proof‑of‑concept (POC) study in mild‑to‑moderate AD (N = 84) – primary endpoint: change in CSF Aβ 42 . | | 2026 | Phase IIb/III – Adaptive design trial (N = 420) evaluating cognitive outcomes (ADAS‑Cog13) and disease‑modifying biomarkers. | The "SONE" designation belongs to S1 NO

This public link is valid for 7 days and shares a thread, including any personal information you added. This link or copies made by others cannot be deleted. If you share with third parties, their policies apply. Can’t copy the link right now. Try again later.

Without more specific information, here are some general types of features that "SONE-214" could have if it were a product or technology:

In digital media tracking, alphanumeric codes structured exactly like "SONE-214" are universally utilized as .