Juq-097

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| Item | Details | |------|----------| | | JUQ‑097 (also referenced in some filings as JQ‑097 ). | | Developer | Janssen Pharmaceuticals (J&J) – the “JUQ” prefix follows Janssen’s internal naming convention for early‑stage CNS‑focused small‑molecule programs. | | Chemical class | Highly selective, non‑peptidic antagonist of the nociceptin/orphanin‑FQ peptide (NOP) receptor (also known as OPRL1 ). | | Molecular weight | ≈ 420 Da (exact value pending final publication). | | Formulation | Oral tablets (10 mg, 30 mg, 60 mg) for Phase II/III trials; a soluble‑capsule version is in pre‑clinical toxicology. | | Target indication(s) | Alcohol Use Disorder (AUD) and Major Depressive Disorder (MDD) with comorbid alcohol misuse . Secondary exploratory programs include opioid‑induced hyperalgesia and post‑traumatic stress disorder (PTSD). |